Benefits of Temporary Intrathecal Baclofen Therapy: Management of Tone and Spasticity

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Intrathecal baclofen in severe spasticity

Aim. To present the principles and applications ofintrathecal bac/o/en treatmentfor spasticity of various origin. Review. Intrathecal bac/o/en (ITB) introduced for thefirst time in 1984, is widely used in the treatment 0/ severe spasticity ofvarious origin. Bac/ofen is delivered via an intrathecal catheterji'om an implantable pump that allows to control the dosage over many years. Numerous repo...

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Efficacy and safety of oral baclofen in the management of spasticity: A rationale for intrathecal baclofen.

Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a rationale for the use of intrathecal baclofen. Results suggest that oral baclofen may be effective in many patients with spasticity, regardless of the...

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Neurosurgical Management of Childhood Spasticity: Functional Posterior Rhizotomy and Intrathecal Baclofen Infusion Therapy

A paradigm shift is currently ongoing in the treatment of spasticity in childhood in Japan. Functional posterior rhizotomy (FPR), which was first introduced to Japan in 1996, is best indicated for children with spastic cerebral palsy, regardless of the clinical severity of spasticity. Surgery is generally carried out in the cauda equina, where the posterior root is separated from the anterior o...

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Functional benefits and cost/benefit analysis of continuous intrathecal baclofen infusion for the management of severe spasticity.

OBJECT Intrathecally delivered baclofen has been used as a treatment for severe spasticity since 1984. Despite this, there are uncertainties surrounding the benefits of treatment and the costs involved. The authors assessed the evidence of benefits and identified costs and the cost/benefit ratio for continuous intrathecal baclofen infusion in the treatment of severe spasticity. METHODS A syst...

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Cost-effectiveness of intrathecal baclofen therapy for the treatment of severe spasticity associated with cerebral palsy.

Spasticity is relatively common among children with cerebral palsy. This condition can be painful, can severely impair a child's ability to perform basic tasks, and can place an enormous emotional and financial burden on the family. Intrathecal baclofen delivered via an implantable pump is an effective treatment option for children unresponsive to oral medication and needing generalized motor c...

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ژورنال

عنوان ژورنال: International Journal of Brain Disorders and Treatment

سال: 2015

ISSN: 2469-5866

DOI: 10.23937/2469-5866/1510003